Prevalence of Submandibular Gland Metastasis in Squamous Cell Carcinomas of Oral Cavity

ABSTRACT Background: The oral squamous cell carcinoma (OSCC), the most common malignant tumor of cavity, have aggressive biological behavior and is treated with surgical excision, lymph node dissection submandibular gland excision. However, rarely involved by OSCC. study aimed to identify prevalence involvement metastasis in cavity patients at a tertiary care center Pakistan. Methods: cancer (139) having wide excisions neck cases were included from Dow Diagnostic Research Reference Laboratory (DDRRL), between May 2017-2019. summary was recorded specifically designed protocol. Data analyzed SPSS version 21. Chi-square test used find an association categorical variables p-value <0.05 considered statistically significant. Results: male female ratio 2.7: 1. A age range (20-84 years) mean 46±13 years. Most 48 (34.5%) belonged >51 years group. frequently sites Buccal mucosa 75 (52.9%), followed tongue 24 (17.45%). significant size thickness (p<0.005), as well histological grade (p=0.023). In this study, only 3 (2.1%) glands metastatic carcinoma. Conclusion: Submandibular very low warrant efforts towards preservation early-stage patients. Keywords: Oral Squamous Cell Carcinoma; Gland; Neck Dissection.